Microscopes have been a great help in the discovery of lots of microorganisms, diseases they caused, antibiotics they can produced and other things that have been useful and harmful to mankind for such long time. Microscopes have evolved from the simple, most basic ones to a more intricate, high-powered and simply innovative type that the inventors, designers and their makers have created. The microscopes have been a very good tool for the scientists, biologists, and other science experts and specialists as well as with the students and the faculty in the aspect of instruction. The microbiologists and other researchers have observed the nature and behaviors of the microorganisms as well as the problems they trigger with the use of the microscopes. There are various microscopes for specific use. There are teaching microscopes like the monocular and binocular compound microscopes, there are also medical and analytical microscopes such as the electron scanning microscopes, light microscopes, metallurgical microscopes, dissecting microscopes, and forensic microscopes. Different types for different purposes and applications. There are also microscopes that can be inserted inside the body to view the internal living organs of an individual in order to detect the disease the individual is suffering from. This is entirely varied from the microscope that is being used to perform biopsy in order to determine the underlying disease of a patient.

The laser-capture micro-dissecting microscope is one of these innovative dissecting microscopes that have been created in order to check the underlying illness of a patient.

The incapability of pathologists to diagnose ovarian cancer in its initial stages has resulted to thousands of death of women. The patient might possibly complain of lower abdominal pain for years that the physicians before might only ignore or take it as an ordinary stomach ache until it came to a point that it became unavoidable due to its intensity and chronicity. At the time the patient would have a surgical referral, the tumor had developed and formed nearly to soccer ball size with numerous metastases. The cancer could be in a terminal stage already. Diagnosed too late and so the patient would die soon. Such sad experience led Dr. Lance A. Liotta to the study the medical science and to the worked on and eventually developed the laser-capture micro-dissecting microscope over the years from 1989 to 1998.

Sick cells propel protein signals into the margins between healthy and unhealthy cells. The laser-capture microscope permits the pathologists to segregate the margins, remove those regions, and determine their protein signals by mass spectroscopy.

When the pathologist recognizes the defining array of protein signals that suggest cancer inside an organ, it becomes probable to search for the same protein signatures in the blood of other patients prior to the formation of a detectable tumor mass. The said early determination together with a surgical solution can be life-saving in majority of the cases.

Though it was a bad and sad experience for the doctor that such a tragedy have happened, still his effort to improve the lives of those people that might be suffering from the such kind of disease has remained undaunted. The dissecting microscope has served a lot of help for those lives that probably be in grave peril.